Papers concerning ozone therapy are in bold characters.
I lavori riguardanti l'ozono terapia sono indicati in carattere neretto.

 

PROF. VELIO BOCCI LIST OF PUBLICATIONS 1990-1999
Elenco delle pubblicazioni 1990-1999 del Prof. Velio Bocci

 

220. BOCCI, V., F. CARRARO, A. NALDINI, E. BORRELLI, G. BIAGI, G. GOTTI, AND P. P. GIOMARELLI. Interferon levels in human pulmonary tumors are lower than plasma levels. J. Biol. Regul. Homeost. Agents 1990; 4: 153-156.

221. BOCCI, V. Catabolism of therapeutic proteins and peptides with implications for drug delivery. Adv. Drug Del. Rev. 1990; 4: 149-169.

222. BOCCI, V., G. P. PESSINA, C. NICOLETTI, AND L. PAULESU. The lymphatic route. VII. Distribution of recombinant human interleukin-2 in rabbit plasma and lymph. J. Biol. Regul. Homeost. Agents 1990; 4: 25-29.

223. BOCCI, V. What is the function of autoantibodies to cytokines? `letter; comment. Immunol. Today 1990; 11: 230.

224. BOCCI, V. Is interferon effective after oral administration? The state of the art. J. Biol. Regul. Homeost. Agents 1990; 4: 81-83.

225. BOCCI, V. AND L. PAULESU. Studies on the biological effects of ozone 1. Induction of interferon gamma on human leucocytes. Haematologica 1990; 75: 510-515.

226. BOCCI, V., F. CARRARO, A. NALDINI, P. P. CAGOL, E. M. PASQUAL, C. PREVALDI, AND D. CASARA. Distribution of human recombinant interferon-alpha 2 in rat plasma, liver, and experimental liver metastases. Mol. Biother. 1990; 2: 233-234.

227. BOCCI, V. Tumor therapy with biological response modifiers. Why is progress slow? EOS - J. Immunol. Immunopharmacol. 1990; 10: 79-82.

228. BOCCI, V., F. CARRARO, A. NALDINI, L. PAULESU, AND G. P. PESSINA. Roles of interferons in physiological conditions and for the control of viral diseases. In: Microbiological, chemotherapeutical and immunological problems in high risk patients, edited by E. Garaci, G. Renzini, F. Filadoro, A. L. Goldstein, and J. Verhoef. New York: Serono Symposia Publication from Raven Press, 1990, p. 243-250.

229. PESSINA, G. P., V. BOCCI, C. NICOLETTI, C. BECHERUCCI, R. PRESENTINI, L. PARENTE, L. VILLA, A. TAGLIABUE, AND D. BORASCHI. Metabolic behavior and distribution of the synthetic nonapeptide fragment 163-171 of human IL-1 beta. Lymphokine Res. 1990; 9: 371-379.

230. BOCCI, V. Absorption of cytokines via oropharyngeal-associated lymphoid tissues. Does an unorthodox route improve the therapeutic index of interferon? Clin. Pharmacokinet. 1991; 21: 411-417.

231. BOCCI, V. Interleukins. Clinical pharmacokinetics and practical implications. Clin. Pharmacokinet. 1991; 21: 274-284.

232. BOCCI, V. What roles have anti-interferon antibodies in physiology and pathology? Res. Clin. Lab. 1991; 21: 79-84.

233. BOCCI, V., K. VON BREMEN, F. CORRADESCHI, E. LUZZI, AND L. PAULESU. What is the role of cytokines in human colostrum? J. Biol. Regul. Homeost. Agents 1991; 5: 121-124.

234. PAULESU, L., E. LUZZI, AND V. BOCCI. Studies on the biological effects of ozone: 2. Induction of tumor necrosis factor (TNF-a ) on human leucocytes. Lymphokine Cytokine Res. 1991; 10: 409-412.

235. PAULESU, L., V. BOCCI, G. P. PESSINA, C. NICOLETTI, M. BOCCANERA, AND A. CASSONE. Interferon induction in rabbits after intraduodenal administration of a phosphorylated glucomannan-protein fraction of the cell wall of Candida albicans. Immunol. Lett. 1991; 27: 231-236.

236. PAULESU, L., G. P. PESSINA, AND V. BOCCI. The gut-associated lymphoid tissue and the placenta: two important sites of physiological interferon response. J. Chemot. 1991; III(suppl.3): 90-92.

237. PAULESU, L., V. BOCCI, A. KING, AND Y. M. LOKE. Immunocytochemical localization of interferons in human trophoblast populations. J. Biol. Regul. Homeost. Agents 1991; 5: 81-85.

238. PAULESU, L., V. BOCCI, C. NICOLETTI, AND G. P. PESSINA. Production of interferon-like activity by gut-associated lymphoid tissue in vivo upon yogurt administration. EOS-J. Immunol. Immunopharmacol. 1991; XI: 149-151.

239 BOCCI, V. Ozonization of blood for the therapy of viral diseases and immunodeficiencies. A hypothesis. Med. Hypotheses 1992; 39: 30-34.

240. BOCCI, V. Physicochemical and biologic properties of interferons and their potential uses in drug delivery systems. Crit. Rev. Ther. Drug Carr. Syst. 1992; 9: 91-133.

241. BOCCI, V. The neglected organ: bacterial flora has a crucial immunostimulatory role. Perspect. Biol. Med. 1992; 35: 251-260.

242. PAULESU, L., G. P. PESSINA, AND V. BOCCI. Human beta-interferon incubated with muscle homogenate is protected by albumin but not by proteinase inhibitors. Proc. Soc. Exp. Biol. Med. 1992; 200: 414-417.

  1. PALESU, L., A. DI STEFANO, E. LUZZI, V. BOCCI, S. SILVESTRI, AND L. NENCIONI. Effect of tuftsin and its retro-inverso analogue on the release of interferon (IFN-gamma) and tumor necrosis factor (TNF-alfa) by human leucocytes. Immunol. Lett. 1992; 34: 7-12.

244. BOCCI, V., E. LUZZI, F. CORRADESCHI, L. PAULESU, AND A. DI STEFANO. Studies on the biological effects of ozone: 3. An attempt to define conditions for optimal induction of cytokines. Lymphokine Cytokine Res. 1993; 12: 121-126.

245. BOCCI, V. Mistletoe (viscum album) lectins as cytokine inducers and immunoadjuvant in tumor therapy. A review. J. Biol. Regul. Homeost. Agents 1993; 7: 1-6.

246. BOCCI, V., L. PAULESU, AND G. P. PESSINA. The renal catabolic pathways of cytokines. In: Kidney, proteins and drugs: an update, edited by C. Bianchi, V. Bocci, F. A. Carone, and R. Rabkin. Basel: Karger, 1993, p. 55-60.

247. BOCCI, V. Interferon. Una storia recente ed antichissima. Fisiopatologia e clinica del sistema interferon. Antea Edizioni, 1993, p. 1-205.

248. BOCCI, V. Endogenous production of interferon: physiological significance and practical implications. In: Lymphoblastoid Interferon. Current aspects and future perspectives. Proceedings of the first int. symposium on lymphoblastoid alpha-interferon, Porto cervo, Sardinia, May 1992, 1993, p. 24-31.

249. BOCCI, V. Gli interferoni. (Edizione aggiornata). In: Medicina Clinica Vol.1, Torino: C.G. Ed. Med. Scient., 1993, p. 657-680.

250. BOCCI, V., K. VON BREMEN, F. CORRADESCHI, F. FRANCHI, E. LUZZI, AND L. PAULESU. Presence of interferon-gamma and interleukin-6 in colostrum of normal women. Lymphokine Cytokine Res. 1993; 12: 21-24.

251. BOCCI, V., F. CARRARO, M. ZEULI, A. NALDINI, AND F. CALABRESI. The lymphatic route. VIII. Distribution and plasma clearance of recombinant human interleukin-2 after SC administration with albumin in patients. Biotherapy 1993; 6: 73-77.

252. BOCCI, V., E. LUZZI, F. CORRADESCHI, L. PAULESU, R. ROSSI, E. CARDAIOLI, AND P. DI SIMPLICIO. Studies on the biological effects of ozone: 4. Cytokine production and glutathione levels in human erythrocytes. J. Biol. Regul. Homeost. Agents 1993; 7: 133-138.

253. NALDINI, A., D. H. CARNEY, V. BOCCI, K. D. KLIMPEL, M. ASUNCION, L. E. SOARES, AND G. R. KLIMPEL. Thrombin enhances T cell proliferative responses and cytokine production. Cell. Immunol. 1993; 147: 367-377.

254. NALDINI, A., F. CARRARO, W. R. FLEISCHMANN,JR., AND V. BOCCI. Hypoxia enhances the antiviral activity of interferons. J. Interferon Res. 1993; 13: 127-132.

255. PESSINA, G. P., L. PAULESU, F. CORRADESCHI, E. LUZZI, M. TANZINI, A. DI STEFANO, G. MATTEUCCI, AND V. BOCCI. Production of tumor necrosis factor a by rat alveolar macrophages collected after acute cigarette smoking. Arch. Immunologiae & Therapie Experimentalis 1993; 41: 343-348.

256. PESSINA, G. P., V. BOCCI, F. CARRARO, A. NALDINI, AND L. PAULESU. The lymphatic route. IX. Distribution of recombinant interferon-a 2 administered subcutaneously with oedematogenic drugs. Physiol. Res. 1993; 42: 243-250.

257. PESSINA, G. P., L. PAULESU, F. CORRADESCHI, E. LUZZI, M. TANZINI, C. ALDINUCCI, A. DI STEFANO, AND V. BOCCI. Chronic cigarette smoking enhances spontaneous release of tumour necrosis factor-a from alveolar macrophages of rats. Mediat. Inflamm. 1993; 2: 423-428.

258. PESSINA, G. P., L. PAULESU, F. CORRADESCHI, E. LUZZI, A. DI STEFANO, M. TANZINI, G. MATTEUCCI, AND V. BOCCI. Effects of acute cigarette smoke exposure on macrophage kinetics and release of tumour necrosis factor a in rats. Mediat. Inflamm. 1993; 2: 119-122.

259. BOCCI, V., E. LUZZI, F. CORRADESCHI, AND L. PAULESU. Studies on the biological effects of ozone: 5. Evaluation of immunological parameters and tolerability in normal volunteers receiving ambulatory autohaemotherapy. Biotherapy 1994; 7: 83-90.

260. BOCCI, V. Autohaemotherapy after treatment of blood with ozone. A reappraisal. J. Int. Med. Res. 1994; 22: 131-144.

261. BOCCI, V. A reasonable approach for the treatment of HIV infection in the early phase with ozonetherapy (autohemotherapy). How inflammatory cytokines may have a therapeutic role. Mediat. Inflamm. 1994; 3: 315-321.

262. BOCCI, V. Understanding the physiology and pharmacology of interferons. Interaction 1994; 2: 20-25.

263. BOCCI, V. Pharmacology and side-effects of interferons. Antivir. Res. 1994; 24: 111-119.

264. NALDINI, A., S. CESARI, AND V. BOCCI. Effects of hypoxia on the cytotoxicity mediated by TNFa . Lymphokine Cytokine Res. 1994; 13: 233-238.

265. BOCCI, V., E. LUZZI, F. CORRADESCHI, AND S. SILVESTRI. Studies on the biological effects of ozone: 6. Production of transforming growth factor b by human blood after ozone treatment. J. Biol. Regul. Homeost. Agents 1994; 8: 108-112.

266. BOCCI, V. Ozonetherapy today. In: Proceedings Ozone in Medicine. 12th World Congress of the International Ozone Association, 15th to 18th May 1995, Lille, France, edited by International Ozone Association. Tours: Instaprint S.A., 1995, p. 13-28.

267. BOCCI, V. Tutte le vocazioni dell’ozono. Il Giornale del Medico 1995; 4:5.

268. NALDINI, A., F. CARRARO, AND V. BOCCI. Effects of hypoxia on the antiproliferative activity of human interferons. J. Interferon and Cytokine Res. 1995; 15:137-142.

269. PESSINA, G. P., L. PAULESU, F. CORRADESCHI, C. ALDINUCCI, E. LUZZI, AND V. BOCCI. Pulmonary catabolism of interferon-g evaluated by lung perfusion of both normal and smoke-exposed rats. J. Interferon and Cytokine Res. 1995; 15:225-230.

270. PESSINA, G. P., L. PAULESU, F. CORRADESCHI, E. LUZZI, C. ALDINUCCI, M. TANZINI, AND V. BOCCI. Pharmacokinetics and catabolism of tumor necrosis factor-a in rat lungs. Immunopharmacology 1995; 29:245-250.

271. BOCCI, V. Immunologische Aspekte - eine kritische Betrachtung aus italianischer Sicht -. In: Ozon - Handbuck. Grundlagen. Prävention. Therapie, edited by Beck and Viebahn-Hänsler. Landsberg: Ecomed, 1995, p. 1-16.

272. BUONOCORE, G., M. DE FILIPPO, D. GIOIA, E. PICCIOLINI, E. LUZZI, V. BOCCI AND R. BRACCI. Maternal and neonatal plasma cytokine levels in relation to mode of delivery. Biol. Neonate 1995; 68:104-110.

273. BORRELLI, E., P. GIOMARELLI, A. NALDINI, E. LUZZI, S. SILVESTRI, M. GARDINALI, AND V. BOCCI. Plasma levels of immunosuppressive mediators during cardiopulmonary bypass. Med.Inflamm. 1996; 5:51-55.

274. BOCCI, V., S. SILVESTRI, F. CORRADESCHI, E. LUZZI, AND C. ALDINUCCI. Verso una razionalizzazione della ozonoterapia. Atti del VI Congresso della Societa' Italiana di Ossigeno-Ozono Terapia, Roma, 29 settembre/10 ottobre 1994. Acta Toxicol.Ther. XVII(2-3): 185-199, 1996.

275. BOCCI V. lettura magistrale: Perché l’ozonoterapia è una pratica medica trascurata. Atti del VI Congresso della Societa' Italiana di Ossigeno-Ozono terapia, Roma, 29 settembre/10 ottobre 1994. Acta Toxicol.Ther. XVII(2-3): 77-82, 1996.

  1. FLORI, M.L., P. RUBEGNI, A.G. D, E. STANGHELLINI, L. ANDREASSI, E. LUZZI, AND V. BOCCI. L'ozono nel trattamento della psoriasi. Atti del VI Congresso della Societa' Italiana di Ossigeno-Ozono terapia, Roma, 29 settembre/10 ottobre 1994. Acta Toxicol.Ther. XVII(2-3): 137-146, 1996.

277. BOCCI, V. Ozone: a mixed blessing. New mechanisms of the action of ozone on blood cells make ozonated major autohaemotherapy (MAH) a rational approach. Forsch.Komplementärmed. 3: 25-33, 1996.

278. BOCCI, V. Does ozone therapy normalize the cellular redox balance? Med.Hypotheses 46: 150-154, 1996.

  1. BOCCI, V. Ozonetherapy has become of age in Russia. Practice of Ozonetherapy 1: 3, 1996.

  2. BOCCI, V. Has Ozonetherapy any future in the West? (Some critical comments). Practice of Ozonetherapy 1: 4-9, 1996.

  3. BOCCI, V. Ozone as a bioregulator. Pharmacology and toxicology of ozonetherapy today. J.Biol.Regulat.Homeost.Agent. 10: 31-53, 1996.


282. PESSINA, G.P., L. PAULESU, F. CORRADESCHI, C. ALDINUCCI, E. LUZZI, AND V. BOCCI. Pulmonary catabolism of interleukin 6 evaluated by lung perfusion of normal and smoker rats. J.Pharm.Pharmacol. 48: 1063-1067, 1996.

283. PESSINA, G.P., C. ALDINUCCI, F. CORRADESCHI, AND V. BOCCI. Both interleukin-1a and tumour necrosis factor-a released by alveolar macrophages are depressed after lipopolysaccharide challenge in chronic smoker rats. Med Sci Res 24: 457-459, 1996.

  1. BOCCI, V. Die senile makulopathie und verwandte erkrankungen. In: Ozon-Handbuch. Grundlagen. Prävention. Therapie, edited by Beck and Viebahn-Hänsler. Landsberg: Ecomed, 1997, p. 1-25.

  2. NALDINI, A., F. CARRARO, S. SILVESTRI, AND V. BOCCI. Hypoxia affects cytokine production and proliferative responses by human peripheral mononuclear cells. J.Cell.Physiol. 173: 335-342, 1997.

  3. BOCCI, V., G. VENTURI, M. CATUCCI, P.E. VALENSIN, AND M. ZAZZI. Lack of efficacy of ozone therapy in HIV infection. Clin.Microbiol.Infec. 4: 667-669, 1998.

287. BOCCI, V., G. VALACCHI, F. CORRADESCHI, AND G. FANETTI. Studies on the biological effects of ozone: 8. Effects on the total antioxidant status and on interleukin-8 production. Mediat.Inflamm. 7: 313-317, 1998.

288. BOCCI, V. Ipotetici meccanismi di azione dell'ozono nel trattamento del conflitto discoradicolare. In: Lombalgie e lombosciatalgie. Criteri di diagnosi e cura, edited by F. Ceccherelli and A. Ricciardi. Torino: Edizioni Libreria Cortina, 1998, p. 331-340.

289. BOCCI, V., G. VALACCHI, F. CORRADESCHI, C. ALDINUCCI, S. SILVESTRI, E. PACCAGNINI, AND R. GERLI. Studies on the biological effects of ozone: 7. Generation of reactive oxygen species (ROS) after exposure of human blood to ozone. J.Biol.Regulat.Homeost.Agent. 12: 67-75, 1998.

290. LEÓN, O.S., S. MENÉNDEZ, N. MERINO, R. CASTILLO, S. SAM, L. PÉREZ, E. CRUZ, AND V. BOCCI. Ozone oxidative preconditioning: a protection against cellular damage by free radicals. Mediat.Inflamm. 7: 289-294, 1998.

291. BOCCI, V. Is ozone therapy therapeutic ? Perspect.Biol.Med. 42: 131-143, 1998.

  1. NALDINI, A., L. SOWER, V. BOCCI, B. MEYERS, AND D.H. CARNEY. Thrombin receptor expression and responsiveness of human monocytic cells to thrombin is linked to interferon-induced cellular differentiation. J.Cell.Physiol. 177: 76-84, 1998.

  2. BOCCI, V. Ozonetherapy as a possible biological response modifier in cancer. Forsch. Komplementärmed. 5: 54-60, 1998.

  3. BARBER, E., S. MENÉNDEZ, O.S. LEÓN, M.O. BARBER, N. MERINO, J.L. CALUNGA, E. CRUZ, AND V. BOCCI. Prevention of renal injury after induction of ozone tolerance in rats submitted to warm ischaemia. Mediat.Inflamm. 8: 37-41, 1999.

  4. BOCCI, V., G. VALACCHI, R. ROSSI, D. GIUSTARINI, E. PACCAGNINI, A.M. PUCCI, AND P. DI SIMPLICIO. Studies on the biological effects of ozone: 9. Effects of ozone on human platelets. Platelets 10: 110-116, 1999.


296. BOCCI, V. The oropharyngeal delivery of interferons. Where are and where do we need to go. J.Interferon Cytokine Res. 1999.(In Press)

  1. BOCCI, V., E. BORRELLI, G. VALACCHI, AND E. LUZZI. Quasi-total body exposure to oxygen-ozone in a sauna cabin. Eur.J.Appl.Physiol. 1999.(In press)

  2. VALACCHI, G. AND V. BOCCI. Studies on the biological effects of ozone: 10. Release of factors from ozonated human platelets. Mediat. Inflamm. 1999.(In Press)

  1. BOCCI, V., N. DI PAOLO, G. GAROSI, C. ALDINUCCI, E. BORRELLI, G. VALACCHI, F. CAPPELLI, L. GUERRI, G. GAVIOLI, F. CORRADESCHI, R. ROSSI, F. GIANNERINI, AND P. DI SIMPLICIO. Ozonation of blood during extracorporeal circulation. I. Rationale, methodology and preliminary studies. Intern. J. Artif. Organs. 1999.(In Press)

  2. BOCCI, V. Ozonetherapy as a complementary medical approach. Where are we and where do we need to go? Ozone Science and Engineering. 1999.(In Press)
    In: International Ozone Symposium, 21-22 ottobre 1999, Basilea.

301. BOCCI, V. Biological and clinical effects of ozone. Has ozonetherapy any future in medicine ? Brit. J. Biomed.Sci. 1999.(In Press)

  1. BOCCI, V., C. ALDINUCCI, E. BORRELLI, G. VALACCHI, A. DIADORI, G. FANETTI, AND F. CORRADESCHI. Ozone in Medicine. J.Altern.Compl.Med. 1999.(Submitted)